Seminars in Spine Surgery
Volume 21, Issue 4 , Pages 246-256, December 2009

The Role of Fusion for Discogenic Axial Back Pain Without Associated Leg Pain, Spondylolisthesis or Stenosis: An Evidence-Based Review

  • Marcus Coe, MD, MS
  • ,
  • Sohail Mirza, MD, MPH

      Affiliations

    • Corresponding Author InformationAddress reprint requests to Sohail Mirza, MD, MPH, Department of Orthopaedics Surgery, Dartmouth Hitchcock Medical Center, 1 Medical Center Drive, Lebanon, NH 03756
  • ,
  • Dilip Sengupta, MD

Department of Orthopaedic Surgery, Dartmouth Hitchcock Medical Center, Lebanon, NH

The objective of this review was to examine the randomized controlled trials evaluating fusion surgery for discogenic axial back pain without associated leg pain, spondylolisthesis, or stenosis. Six studies were reviewed: 4 that considered spinal fusion in comparison with nonoperative treatment, and 2 that considered fusion in comparison with artificial disc replacement. We found that methodological difficulties limit the ability to draw definitive conclusions, but that fusion appears superior to unstructured nonoperative treatment, similar to structured nonoperative treatment, and similar to short-term results of artificial disc replacement. Further long term, well-constructed randomized controlled trials are warranted.

Keywords: back pain, fusion, disc replacement, randomized controlled trials

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PII: S1040-7383(09)00072-0

doi:10.1053/j.semss.2009.08.008

Seminars in Spine Surgery
Volume 21, Issue 4 , Pages 246-256, December 2009